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Human S100 Calcium Binding Protein A8 (S100A8) ELISA Kit

Cat no: KTE60760


Supplier: Abbkine Scientific Co.Ltd.
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S100A8, a protein associated with a wide variety of inflammatory conditions, is heavily over-expressed in association with inflammation. Human S100A8 possesses neutrophil-repelling properties that result in an anti-inflammatory effect in vivo. The chemotactic activity of S100A8 on neutrophils was tested in Transwell chemotaxis assays. Analysis of the data indicates that S100A8 causes a repulsion of peripheral neutrophils, an activity that S100A8 loses upon its oxidation. S100A8 causes a strong anti-inflammatory effect in the rat air-pouch model of inflammation in vivo. These data highlight a naturally occurring novel anti-inflammatory pathway and provide potential molecular targets for the development of novel anti-inflammatory therapeutics.
Catalogue number: KTE60760
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: P05109
Gene: 6279
Additional info: Human S100 Calcium Binding Protein A8 (S100A8) ELISA Kit has high sensitivity and excellent specificity for detection of Human S100A8. No significant cross-reactivity or interference between Human S100A8 and analogues was observed.

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