Human S100 calcium binding protein B (S-100B) ELISA Kit

S100 proteins are localized in the cytoplasm and nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100B is glial-specific and is expressed primarily by astrocytes, but not all astrocytes express S100B. It has been shown that S100B is only expressed by a subtype of mature astrocytes that ensheath blood vessels and by NG2-expressing cells. This protein may function in neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. In the developing CNS it acts as a neurotrophic factor and neuronal survival protein.

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SPECIFICATIONS

Catalog Number

KTE60758

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

6285

Accession

P04271

Additional Info

Human S100 calcium binding protein B (S-100B) ELISA Kit has high sensitivity and excellent specificity for detection of Human S-100B. No significant cross-reactivity or interference between Human S-100B and analogues was observed.