Human Secretogranin-2 (SCG2) ELISA Kit

SCG2 is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Studies in rodents suggest that the full-length protein, secretogranin II, is involved in the packaging or sorting of peptide hormones and neuropeptides into secretory vesicles. The full-length protein is cleaved to produce the active peptide secretoneurin, which exerts chemotaxic effects on specific cell types, and EM66, whose function is unknown.SCG2 also has 9 potential dibasic cleavage sites, an N-glycosylation site not found in the bovine protein, and a putative sulfation site (tyr121). SCG2 was predicted to assume a secondary structure of alternating helix and turn structures over 45% and 40% of its length, respectively. The authors suggested that this structure may coordinate calcium.

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SPECIFICATIONS

Catalog Number

KTE60744

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

7857

Accession

P13521

Additional Info

Human Secretogranin-2 (SCG2) ELISA Kit has high sensitivity and excellent specificity for detection of Human SCG2. No significant cross-reactivity or interference between Human SCG2 and analogues was observed.