Human Secretory immunoglobulin A (SIgA) ELISA Kit

Secretory IgA (IgA) consists of two IgA monomers joined by the J-chain and furthermore a secretory component. It is secreted in plasma cells based in the lamina propia of mucosal membranes. Synthesis of IgA is independent from the synthesis of serum IgA. This means lack of serum IgA does not necessarily mean a lack of IgA.\nIgA is found in secretions in a specific form called secretory IgA', Secretory IgA is the major immunoglobulin in saliva, tears, colostrum, nasal mucous, motherВґs milk, tracheobronchial and gastrointestinal secretes. It plays a major role in preventing adherence of microorganisms to mucosal sites, in activation of the alternative complement pathway and in activating inflammatory reactions. Newborns are provided with IgA by motherВґs milk and are passively immunized against gastrointestinal infections.

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SPECIFICATIONS

Catalog Number

KTE60664

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Additional Info

Human Secretory immunoglobulin A (SIgA) ELISA Kit has high sensitivity and excellent specificity for detection of Human SIgA. No significant cross-reactivity or interference between Human SIgA and analogues was observed.