Human Semaphorin 3A (SEMA3A) ELISA Kit

SEMA3A is a member of the semaphorin family and encodes a protein with an Ig-like C2-type (immunoglobulin-like) domain, a PSI domain and a Sema domain. This secreted protein can function as either a chemorepulsive agent, inhibiting axonal outgrowth, or as a chemoattractive agent, stimulating the growth of apical dendrites. In both cases, the protein is vital for normal neuronal pattern development. Increased expression of this protein is associated with schizophrenia and is seen in a variety of human tumor cell lines. Also, aberrant release of this protein is associated with the progression of Alzheimer's disease.The first of the CRMP proteins, CRMP2, was identified as an intracellular messenger required for the growth cone-collapse induced by semaphorin 3A.

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SPECIFICATIONS

Catalog Number

KTE60717

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

10371

Accession

Q14563

Additional Info

Human Semaphorin 3A (SEMA3A) ELISA Kit has high sensitivity and excellent specificity for detection of Human SEMA3A. No significant cross-reactivity or interference between Human SEMA3A and analogues was observed.