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Human Semaphorin-4B (SEMA4B) ELISA Kit

Cat no: KTE60712

Human Semaphorin-4B (SEMA4B) ELISA Kit

Semaphorin-4B is a protein encoded by the SEMA4B gene. Members of the collapsin/semaphorin gene family have been proposed to act as growth cone guidance signals in vertebrates and invertebrates. To identify candidate molecules involved in axonal pathfinding during mouse embryogenesis, isolated cDNAs encoding five new members of the semaphorin family (Sem A-Sem E). The murine semaphorin genes are differentially expressed in mesoderm and neuroectoderm before and during the time when axons select their pathways in the embryo. In explant cultures, recombinant Sem D/collapsin converts a matrix permissive for axonal growth into one that is inhibitory for neurites of peripheral ganglia. Semaphorins are a diverse family of molecules that may provide local signals to specify territories nonaccessible for growing axons.

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SPECIFICATIONS

Catalog Number

KTE60712

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

10509

Accession

Q9NPR2

Additional Info

Human Semaphorin-4B (SEMA4B) ELISA Kit has high sensitivity and excellent specificity for detection of Human SEMA4B. No significant cross-reactivity or interference between Human SEMA4B and analogues was observed.

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