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Human Serglycin (SRGN) ELISA Kit

Cat no: KTE60357

Human Serglycin (SRGN) ELISA Kit

Serglycin is a protein best known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of many hematopoietic cells also contain a protease-resistant peptide core, which may be important for neutralizing hydrolytic enzymes. This encoded protein was found to be associated with the macromolecular complex of granzymes and perforin, which may serve as a mediator of granule-mediated apoptosis.Serglycin plays a role in formation of mast cell secretory granules and mediates storage of various compounds in secretory vesicles. Required for storage of some proteases in both connective tissue and mucosal mast cells and for storage of granzyme B in T lymphocytes. Plays a role in localizing neutrophil elastase in azurophil granules of neutrophils. Mediates processing of MMP2.

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SPECIFICATIONS

Catalog Number

KTE60357

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

5552

Accession

P10124

Additional Info

Human Serglycin (SRGN) ELISA Kit has high sensitivity and excellent specificity for detection of Human SRGN. No significant cross-reactivity or interference between Human SRGN and analogues was observed.

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