Human Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform (PPP3CB) ELISA Kit

Cat no: KTE61190

Supplier: Abbkine Scientific Co.Ltd.

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Calcineurin, a calmodulin-regulated protein phosphatase, is found in the cells of all eukaryotes ranging from yeast to mammals. Wang et al. (1996) described this heterodimeric protein as having a 19-kD Ca(2+)-binding regulatory subunit, calcineurin B, and a 58- to 59-kD catalytic subunit, calcineurin A. One gene encodes calcineurin B (PPP3R1) in all tissues except testis, and it is highly conserved at the level of both protein and DNA sequences in eukaryotes. In contrast, there are 2 major isoforms, alpha (PPP3CA) and beta (PPP3CB), of calcineurin A encoded by separate genes located on different human chromosomes. A third isoform, A-gamma (PPP3CC), is unique to testis. Additional diversity of calcineurin A is created by alternative splicing of mRNAs.

Catalogue number:	KTE61190
Reactivities:	Human
Applications:	ELISA
Size:	48T, 96T, 96T5, 96T50
Accession:	P16298
Gene:	5532
Additional info:	Human Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform (PPP3CB) ELISA Kit has high sensitivity and excellent specificity for detection of Human PPP3CB. No significant cross-reactivity or interference between Human PPP3CB and analogues was observed.

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Human Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform (PPP3CB) ELISA Kit

Cat no: KTE61190

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