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Human Shadow of prion protein (SPRN) ELISA Kit

Human Shadow of prion protein (SPRN) ELISA Kit

Cat no: KTE60345

Supplier: Abbkine Scientific Co.Ltd.
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SPRN expression in human, rat, and mouse brain. The deduced human protein contains 151 amino acids. The mammalian proteins share 81 to 95% sequence identity. Alignment of all fish and mammalian Sho proteins showed that all have an N-terminal peptide sequence with an endoplasmic reticulum targeting signal for extracellular transport, a basic RG-rich region, a hydrophobic stretch in the middle of the protein that contains the same unusual composition of small aliphatic residues (GAV) as PrP and PrP-like proteins, and a C-terminal region with a putative N-glycosylation site and a possible GPI anchor site (Premzl et al., 2003, 2004). Database searches revealed that SPRN is expressed in mouse and rat embryo, brain, and retina, in human hippocampus, and in zebrafish embryo and retina.
Catalogue number: KTE60345
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: Q5BIV9
Gene: 503542
Additional info: Human Shadow of prion protein (SPRN) ELISA Kit has high sensitivity and excellent specificity for detection of Human SPRN. No significant cross-reactivity or interference between Human SPRN and analogues was observed.

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