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Human Sialic acid-binding Ig-like lectin 10 (SIGLEC10) ELISA Kit

Human Sialic acid-binding Ig-like lectin 10 (SIGLEC10) ELISA Kit

Cat no: KTE60662

Supplier: Abbkine Scientific Co.Ltd.
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By searching an EST database for sequences resembling CD33 (SIGLEC3) and screening a spleen cDNA library, Munday et al. (2001) isolated a cDNA encoding SIGLEC10. Sequence analysis predicted that the 697-amino acid SIGLEC10 protein contains a signal peptide, an N-terminal V-set Ig-like domain and 4 C2-set Ig-like domains, 5 potential N-linked glycosylation sites, a transmembrane region, and a 126-residue cytoplasmic tail with 3 putative ITIMs. Northern blot analysis detected a major 3.0-kb SIGLEC10 transcript, with highest levels in spleen, lymph node, blood leukocytes, and appendix. Little or no expression was observed in pancreas, thyroid, and testis. Flow cytometric analysis demonstrated eosinophil-specific expression of SIGLEC10, but at a lower level than that of SIGLEC8.
Catalogue number: KTE60662
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: Q96LC7
Gene: 89790
Additional info: Human Sialic acid-binding Ig-like lectin 10 (SIGLEC10) ELISA Kit has high sensitivity and excellent specificity for detection of Human SIGLEC10. No significant cross-reactivity or interference between Human SIGLEC10 and analogues was observed.

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