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Human Signal recognition particle 54 kDa protein (SRP54) ELISA Kit

Cat no: KTE60364


Supplier: Abbkine Scientific Co.Ltd.
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The signal recognition particle (SRP) is a ribonucleoprotein complex that mediates the targeting of proteins to the endoplasmic reticulum (ER). The complex consists of a 7S (or 7SL) RNA and 6 different proteins, SRP9 , SRP14, SRP19, SRP54, SRP68, and SRP72. SRP54 is positioned at the exit site close to ribosomal proteins L23a and L35. When SRP54 contacts the signal recognition particle receptor, SRP54 is rearranged such that it is no longer close to L23a. This repositioning may allow the translocon to dock with the ribosome, leading to insertion of the signal peptide into the translocation channel.SRP54 binds to SRP RNA via the M-domain, but only in the presence of RNA-bound SRP19, and that it associates with the signal peptide of nascent polypeptide chains.
Catalogue number: KTE60364
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: P61011
Gene: 6729
Additional info: Human Signal recognition particle 54 kDa protein (SRP54) ELISA Kit has high sensitivity and excellent specificity for detection of Human SRP54. No significant cross-reactivity or interference between Human SRP54 and analogues was observed.

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