Human Signal transducer and activator of transcription 2 (STAT2) ELISA Kit

Signal transducer and activator of transcription 2 is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly.\nTranscription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus.

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SPECIFICATIONS

Catalog Number

KTE60376

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

6773

Accession

P52630

Additional Info

Human Signal transducer and activator of transcription 2 (STAT2) ELISA Kit has high sensitivity and excellent specificity for detection of Human STAT2. No significant cross-reactivity or interference between Human STAT2 and analogues was observed.