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Human Signal transducer and activator of transcription 5 (STAT5) ELISA Kit

Cat no: KTE60379


Supplier: Abbkine Scientific Co.Ltd.
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STAT5A is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells.
Catalogue number: KTE60379
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: P42229
Gene: 6776
Additional info: Human Signal transducer and activator of transcription 5 (STAT5) ELISA Kit has high sensitivity and excellent specificity for detection of Human STAT5A. No significant cross-reactivity or interference between Human STAT5A and analogues was observed.

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