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Human SLAM family member 7 (SLAMF7) ELISA Kit

Cat no: KTE60645

Human SLAM family member 7 (SLAMF7) ELISA Kit

Sequence analysis predicted that the 335-amino acid transmembrane protein has a 225-residue extracellular domain, which has 7 putative N-linked glycosylation sites, and an 85-amino acid cytoplasmic domain, which contains 2 of the consensus tyrosine motifs and a third C-terminal tyrosine motif that has phe instead of thr.\nFunctional analysis indicated that CRACC mediates lysis that is in addition to that mediated by NKP46 or CD16. Further analysis determined that, unlike CD244, cytotoxicity mediated by CRACC or NKP46 is SAP-independent and that CRACC triggers ERK activation. Immunoblot analysis showed that CRACC is tyrosine phosphorylated in activated NK cells and is associated with 19- and 39-kD proteins.

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SPECIFICATIONS

Catalog Number

KTE60645

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

57823

Accession

Q9NQ25

Additional Info

Human SLAM family member 7 (SLAMF7) ELISA Kit has high sensitivity and excellent specificity for detection of Human SLAMF7. No significant cross-reactivity or interference between Human SLAMF7 and analogues was observed.

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