Human Small proline-rich protein 2B (SPRR2B) ELISA Kit

SPRR genes encode a novel class of polypeptides called small proline-rich proteins that are strongly induced during differentiation of human epidermal keratinocytes in vitro and in vivo. SPRR genes constitute a distinct class of cornified envelope precursor proteins.\nGibbs et al. (1993) concluded that there are 7 genes for the SPRR2 subfamily of small proline-rich proteins, including SPRR2B.Using DNA microarray analysis, Zimmermann et al. (2005) identified Sprr2a and Sprr2b as allergen-induced genes in a mouse model of experimental asthma.By analysis of human-rodent hybrid cell lines and FISH, Gibbs et al. (1993) determined that all SPRR genes, including SPRR2B, are closely linked within a 300-kb DNA segment on chromosome 1q21-q22.

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SPECIFICATIONS

Catalog Number

KTE60349

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

6701

Accession

P35325

Additional Info

Human Small proline-rich protein 2B (SPRR2B) ELISA Kit has high sensitivity and excellent specificity for detection of Human SPRR2B. No significant cross-reactivity or interference between Human SPRR2B and analogues was observed.