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Human Sodium/glucose cotransporter 2 (SLC5A2) ELISA Kit

Human Sodium/glucose cotransporter 2 (SLC5A2) ELISA Kit

Cat no: KTE60597

Supplier: Abbkine Scientific Co.Ltd.
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The major reabsorptive mechanism for D-glucose in the kidney is known to involve a lower affinity, high capacity Na(+)/glucose cotransporter, which is located in the early proximal convoluted tubule segment S1 and has a Na(+)-to-glucose coupling ratio of 1:1.Uptake experiments using cRNA-injected Xenopus oocytes showed specific uptake of glucose and alpha-methyl glucopyranoside at up to three times background. This uptake was saturable, suggesting that the cDNA corresponds to a low-affinity kidney sodium-glucose transporter. It was therefore referred to as sodium-glucose cotransporter 2, or SGLT2. SGLT2 mediates saturable Na(+)-dependent and phlorizin-sensitive transport with K(m) values consistent with low affinity Na(+)/glucose cotransport.
Catalogue number: KTE60597
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: P31639
Gene: 6524
Additional info: Human Sodium/glucose cotransporter 2 (SLC5A2) ELISA Kit has high sensitivity and excellent specificity for detection of Human SLC5A2. No significant cross-reactivity or interference between Human SLC5A2 and analogues was observed.

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