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Human Sodium/hydrogen exchanger 1 (SLC9A1) ELISA Kit

Cat no: KTE60584

Human Sodium/hydrogen exchanger 1 (SLC9A1) ELISA Kit

The antiporter is a ubiquitous membrane-bound enzyme involved in volume- and pH-regulation of vertebrate cells. It is inhibited by the non-specific diuretic drug amiloride and activated by a variety of signals including growth factors, mitogens, neurotransmitters, tumor promoters, and others.The gene was first disrupted in mouse fibroblasts. The lost function was then restored by transfection with human genomic DNA. Clones containing these specific human sequences were isolated. One genomic fragment was identified as an exon-coding sequence from the sodium-hydrogen ion antiporter gene by demonstration that it could complement antiporter deficiency in mouse cells; that it recognized an mRNA in cells expressing antiport activity but not in deficient cells; and that it was amplified in variants overexpressing antiport activity.

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SPECIFICATIONS

Catalog Number

KTE60584

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

6548

Accession

P19634

Additional Info

Human Sodium/hydrogen exchanger 1 (SLC9A1) ELISA Kit has high sensitivity and excellent specificity for detection of Human SLC9A1. No significant cross-reactivity or interference between Human SLC9A1 and analogues was observed.

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