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Human Sodium/iodide cotransporter (SLC5A5) ELISA Kit

Human Sodium/iodide cotransporter (SLC5A5) ELISA Kit

Cat no: KTE60596

Supplier: Abbkine Scientific Co.Ltd.
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The sodium-iodide symporter (NIS) is an ion pump that actively transports iodide (I-) across the basolateral membrane into thyroid epithelial cells. The NIS a member of the sodium/solute symporter family.Active transport of iodine into the thyroid gland is an important step in the process of iodide organification and the formation of triiodothyronine (T3) and thyroxine (T4). The symporter is stimulated by TSH, thereby increasing iodine uptake and iodination of tyrosine.The pump symports two sodium ions for every iodide ion. This symporter is driven by low internal sodium concentration in the thyroid epithelial cells, via facilitated diffusion, caused by the sodium/potassium ATPase pump.This pump is the target of certain anion based inhibitors such as perchlorate, pertechnetate, and thiocyanate.
Catalogue number: KTE60596
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: Q92911
Gene: 6528
Additional info: Human Sodium/iodide cotransporter (SLC5A5) ELISA Kit has high sensitivity and excellent specificity for detection of Human SLC5A5. No significant cross-reactivity or interference between Human SLC5A5 and analogues was observed.

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