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Human Sphingomyelin phosphodiesterase 2 (SMPD2) ELISA Kit

Human Sphingomyelin phosphodiesterase 2 (SMPD2) ELISA Kit

Cat no: KTE60566

Supplier: Abbkine Scientific Co.Ltd.
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SMPD2 isa protein which was initially identified as a sphingomyelinase based on sequence similarity between bacterial sphingomyelinases and a yeast protein. Subsequent studies showed that its biological function is less likely to be as a sphingomyelinase and instead as a lysophospholipase. Neutral sphingomyelinase (N-SMase) activity was first described in fibroblasts from patients with Niemann-Pick disease – a lysosomal storage disease characterized by deficiencies in acid SMase . Subsequent study found that this enzyme was the product of a distinct gene, had an optimum pH of 7.4, was dependent on Mg2+ ions for activity, and was particularly enriched in brain .
Catalogue number: KTE60566
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: O60906
Gene: 6610
Additional info: Human Sphingomyelin phosphodiesterase 2 (SMPD2) ELISA Kit has high sensitivity and excellent specificity for detection of Human SMPD2. No significant cross-reactivity or interference between Human SMPD2 and analogues was observed.

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