Human Sphingosine 1-phosphate receptor type 1 (S1P1) ELISA Kit

S1PR1 (sphingosine-1-phosphate receptor 1) also known as S1P1 and EDG1 (endothelial differentiation gene 1) is a protein encoded by the S1PR1 gene. S1PR1 encodes a G-protein-coupled receptor which binds the lipid signaling molecule sphingosine 1-phosphate (S1P).\nThe protein is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells. It binds the ligand sphingosine-1-phosphate with high affinity and high specificity, and suggested to be involved in the processes that regulate the differentiation of endothelial cells. Activation of this receptor induces cell-cell adhesion.Endothelial cells, and to a lesser extent, in vascular smooth muscle cells, fibroblasts, melanocytes, and cells of epithelioid origin.

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SPECIFICATIONS

Catalog Number

KTE60756

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

1901

Accession

P21453

Additional Info

Human Sphingosine 1-phosphate receptor type 1 (S1P1) ELISA Kit has high sensitivity and excellent specificity for detection of Human S1PR1. No significant cross-reactivity or interference between Human S1PR1 and analogues was observed.