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Human Spleen tyrosine kinase (SYK) ELISA Kit

Cat no: KTE60410

Human Spleen tyrosine kinase (SYK) ELISA Kit

SYKis a member of the Syk family of tyrosine kinases. While Syk and Zap-70 are primarily expressed in hematopoietic tissues, there is expression of Syk in a variety of tissues. Within B and T cells respectively, Syk and Zap-70 transmit signals from the B-Cell receptor and T-Cell receptor. Syk plays a similar role in transmitting signals from a variety of cell surface receptors including CD74, Fc Receptor, and integrins. The role of Syk in epithelial malignancies is controversial. Several authors have suggested that abnormal Syk function facilitates transformation in Nasopharyngeal carcinoma and head and neck cancer while other authors have suggested a tumor suppressor role in breast and gastric cancer.

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SPECIFICATIONS

Catalog Number

KTE60410

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

6850

Accession

P43405

Additional Info

Human Spleen tyrosine kinase (SYK) ELISA Kit has high sensitivity and excellent specificity for detection of Human SYK. No significant cross-reactivity or interference between Human SYK and analogues was observed.

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