Human STE20/SPS1-related proline-alanine-rich protein kinase (STK39) ELISA Kit

STK39 encodes a serine/threonine kinase that is thought to function in the cellular stress response pathway. The kinase is activated in response to hypotonic stress, leading to phosphorylation of several cation-chloride-coupled cotransporters. The deduced 547-amino acid protein has a calculated molecular mass of 59.6 kD. STK39 contains an N-terminal series of proline and alanine repeats (PAPA box), followed by a serine/threonine kinase catalytic domain, a nuclear localization signal, a consensus caspase cleavage recognition motif, and a C-terminal region. Northern blot analysis detected ubiquitous expression of a 3.8-kb transcript, with most abundant expression in brain and pancreas. Western blot analysis of mouse tissues detected a protein of about 60 kD in all tissues examined.

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SPECIFICATIONS

Catalog Number

KTE60390

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

27347

Accession

Q9UEW8

Additional Info

Human STE20/SPS1-related proline-alanine-rich protein kinase (STK39) ELISA Kit has high sensitivity and excellent specificity for detection of Human STK39. No significant cross-reactivity or interference between Human STK39 and analogues was observed.