Human Striatin-4 (STRN4) ELISA Kit

Zinedin, a "novel" protein described here, and SG2NA share with striatin identical protein-protein interaction domains and the same overall domain structure. A phylogenetic analysis supports the hypothesis that they constitute a multigenic family deriving from an ancestral gene. DNA probes and antibodies raised against specific domains of each protein showed that zinedin is mainly expressed in the central nervous system, whereas SG2NA, of more widespread occurrence, is mainly expressed in the brain and muscle. All three proteins are both cytosolic and membrane-bound. All three bind calmodulin in the presence of Ca(2+). In rat brain, SG2NA and striatin are generally not found in the same neurons. Both localize to the soma and dendrites, suggesting that they share a similar type of addressing and closely related functions.

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SPECIFICATIONS

Catalog Number

KTE60395

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

29888

Accession

Q9NRL3

Additional Info

Human Striatin-4 (STRN4) ELISA Kit has high sensitivity and excellent specificity for detection of Human STRN4. No significant cross-reactivity or interference between Human STRN4 and analogues was observed.