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Human Sucrase-isomaltase, intestinal (SI) ELISA Kit

Human Sucrase-isomaltase, intestinal (SI) ELISA Kit

Cat no: KTE60665

Supplier: Abbkine Scientific Co.Ltd.
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Congenital sucrase-isomaltase deficiency is an example of a disease in which mutation results in transport-incompetent molecules. sucrase-isomaltase is not transported to the brush border membrane but accumulates as a mannose-rich precursor in the endoplasmic reticulum, ER-Golgi intermediate compartment, and the cis-Golgi, where it is finally degraded. The enzyme consists of 2 subunits which are synthesized as a single chain mannose-rich precursor. From studies of the cDNA, the human protein has 83% identity with the rabbit enzyme. In addition to the previously reported homology with lysosomal alpha-glucosidase, the sucrase and isomaltase subunits appear to be homologous to a yeast glucoamylase.
Catalogue number: KTE60665
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: P14410
Gene: 6476
Additional info: Human Sucrase-isomaltase, intestinal (SI) ELISA Kit has high sensitivity and excellent specificity for detection of Human SI. No significant cross-reactivity or interference between Human SI and analogues was observed.

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