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Human Synaptotagmin-12 (SYT12) ELISA Kit

Cat no: KTE60427

Human Synaptotagmin-12 (SYT12) ELISA Kit

Syt12 colocalises with and binds Syt1 on synaptic vesicles, but regulates spontaneous release independently from Syt1. Syt12 is phosphorylated by cAMP-dependent protein kinase A (PKA) at a single site, and mutation of this site blocks the effect of Syt12 on spontaneous release. Syt12 is not essential for basal synaptic transmission, but is required for cAMP-dependent mossy fibre long-term potentiation (LTP), a presynaptic form of long-term plasticity that is induced by PKA activation

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SPECIFICATIONS

Catalog Number

KTE60427

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

91683

Accession

Q8IV01

Additional Info

Human Synaptotagmin-12 (SYT12) ELISA Kit has high sensitivity and excellent specificity for detection of Human SYT12. No significant cross-reactivity or interference between Human SYT12 and analogues was observed.

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