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Human T cell immunoreceptor with Ig and ITIM domains (TIGIT) ELISA Kit

Cat no: KTE62327

Human T cell immunoreceptor with Ig and ITIM domains (TIGIT) ELISA Kit

TIGIT encodes a member of the PVR (poliovirus receptor) family of immunoglobin proteins. The product of this gene is expressed on several classes of T cells including follicular B helper T cells (TFH). The protein has been shown to bind PVR with high affinity; this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses.\nThe predicted 244-amino acid TIGIT protein has a single Ig domain, followed by a type I transmembrane domain and a single intracellular immunoreceptor tyrosine-based inhibitory motif. It shares 88%, 67%, and 58% amino acid identity with its rhesus, dog, and mouse homologs, respectively.

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SPECIFICATIONS

Catalog Number

KTE62327

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

201633

Accession

Q495A1

Additional Info

Human T cell immunoreceptor with Ig and ITIM domains (TIGIT) ELISA Kit has high sensitivity and excellent specificity for detection of Human TIGIT. No significant cross-reactivity or interference between Human TIGIT and analogues was observed.

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