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Human T-H glycoprotein (THP) ELISA Kit

Human T-H glycoprotein (THP) ELISA Kit

Cat no: KTE60088

Supplier: Abbkine Scientific Co.Ltd.
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Uromodulin, the most abundant protein in normal urine. Its excretion in urine follows proteolytic cleavage of the ectodomain of its glycosyl phosphatidylinosital-anchored counterpart that is situated on the luminal cell surface of the loop of Henle. Uromodulin may act as a constitutive inhibitor of calcium crystallization in renal fluids. Excretion of uromodulin in urine may provide defense against urinary tract infections caused by uropathogenic bacteria. Defects in this gene are associated with the autosomal dominant renal disorders medullary cystic kidney disease-2 and familial juvenile hyperuricemic nephropathy. These disorders are characterized by juvenile onset of hyperuricemia, gout, and progressive renal failure. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date.
Catalogue number: KTE60088
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: P07911
Gene: 7369
Additional info: Human T-H glycoprotein (THP) ELISA Kit has high sensitivity and excellent specificity for detection of Human UMOD. No significant cross-reactivity or interference between Human UMOD and analogues was observed.

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