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Human Tapasin (TAPBP) ELISA Kit

Human Tapasin (TAPBP) ELISA Kit

Cat no: KTE60473

Supplier: Abbkine Scientific Co.Ltd.
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TAPBP encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and TAPBP may be bound to a single TAP molecule. Tapasin contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms.
Catalogue number: KTE60473
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: O15533
Gene: 6892
Additional info: Human Tapasin (TAPBP) ELISA Kit has high sensitivity and excellent specificity for detection of Human TAPBP. No significant cross-reactivity or interference between Human TAPBP and analogues was observed.

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