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Human Tensin-3 (TNS3) ELISA Kit

Human Tensin-3 (TNS3) ELISA Kit

Cat no: KTE60173

Supplier: Abbkine Scientific Co.Ltd.
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Tensin-3 formed a complex with focal adhesion kinase and p130Cas (BCAR1) in human breast carcinoma cells. Addition of EGF to these cells induced dephosphorylation of FAK and p130Cas, leading to dissociation of the tensin-3/FAK/p130Cas complex and enhanced interaction between tensin-3 and EGFR. The deduced 1,445-amino acid protein has a calculated molecular mass of 155.3 kD. Like other tensins, tensin-3 has an N-terminal actin-binding domain and C-terminal SH2 and PTB domains. It also has several potential tyrosine phosphorylation sites. Northern blot analysis detected high expression of an 8-kb transcript in kidney and placenta, with weaker expression in heart, skeletal muscle, spleen, liver, and lung. Western blot analysis revealed a 180-kD tensin-3 protein in human endothelial and epithelial cells and fibroblasts.
Catalogue number: KTE60173
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: Q68CZ2
Gene: 64759
Additional info: Human Tensin-3 (TNS3) ELISA Kit has high sensitivity and excellent specificity for detection of Human TNS3. No significant cross-reactivity or interference between Human TNS3 and analogues was observed.

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