Human TERF1-interacting nuclear factor 2 (TINF2) ELISA Kit

Cat no: KTE60322

Supplier: Abbkine Scientific Co.Ltd.

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TINF2 encodes one of the proteins of the shelterin, or telosome, complex which protects telomeres by allowing the cell to distinguish between telomeres and regions of DNA damage. The protein encoded by this gene is a critical part of shelterin; it interacts with the three DNA-binding proteins of the shelterin complex, and it is important for assembly of the complex. Mutations in this gene cause dyskeratosis congenita (DKC), an inherited bone marrow failure syndrome.The TIN2 open reading frame encoded a protein of 354 amino acids. A wide variety of human tissues and cell types expressed a 2.4-kb TIN2 transcript on Northern blot analysis, and expression did not vary with growth state, immortalization, or transformation. TIN2 interacted with TRF1 in vitro and in cells, and colocalized with TRF1 in nuclei and metaphase chromosomes.

Catalogue number:	KTE60322
Reactivities:	Human
Applications:	ELISA
Size:	48T, 96T, 96T5, 96T50
Accession:	Q9BSI4
Gene:	26277
Additional info:	Human TERF1-interacting nuclear factor 2 (TINF2) ELISA Kit has high sensitivity and excellent specificity for detection of Human TINF2. No significant cross-reactivity or interference between Human TINF2 and analogues was observed.

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Human TERF1-interacting nuclear factor 2 (TINF2) ELISA Kit

Cat no: KTE60322

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