Human Thioredoxin reductase (TRXR) ELISA Kit

Thioredoxin reductase 1, cytoplasmic is a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine (Sec) residue which is required for catalytic activity. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenocysteine-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in several transcript variants encoding the same or different isoforms.

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SPECIFICATIONS

Catalog Number

KTE62634

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

7296

Accession

Q16881

Additional Info

Human Thioredoxin reductase (TRXR) ELISA Kit has high sensitivity and excellent specificity for detection of Human TXNRD1. No significant cross-reactivity or interference between Human TXNRD1 and analogues was observed.