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Human Thymidylate synthase (TYMS) ELISA Kit

Human Thymidylate synthase (TYMS) ELISA Kit

Cat no: KTE60109

Supplier: Abbkine Scientific Co.Ltd.
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Thymidylate synthetase (EC 2.1.1.45) is the enzyme used to generate thymidine monophosphate (dTMP), which is subsequently phosphorylated to thymidine triphosphate for use in DNA synthesis and repair. By means of reductive methylation, deoxyuridine monophosphate (dUMP) and N5,N10-methylene tetrahydrofolate are together used to form dTMP, yielding dihydrofolate as a secondary product. As an anti-cancer chemotherapy target, thymidylate synthetase can be inhibited by the thymidylate synthase inhibitors such as fluorinated pyrimidine fluorouracil, or certain folate analogues, including most notably raltitrexed (trade name Tomudex).
Catalogue number: KTE60109
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: P04818
Gene: 7298
Additional info: Human Thymidylate synthase (TYMS) ELISA Kit has high sensitivity and excellent specificity for detection of Human TYMS. No significant cross-reactivity or interference between Human TYMS and analogues was observed.

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