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Human Thymidylate synthetase (TS) ELISA Kit

Cat no: KTE60126

Human Thymidylate synthetase (TS) ELISA Kit

Tuberous sclerosis protein 1, also known as TSC1 or hamartin, This peripheral membrane protein was implicated as a tumor suppressor. It may be also involved in vesicular transport and docking, in complex with TSC2.Defects in this gene may cause tuberous sclerosis, due to a functional impairment of the hamartin-tuberin complex. Defects in TSC1 may also be a cause of focal cortical dysplasia.In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Seems not to be required for TSC2 GAP activity towards RHEB. Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling.

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SPECIFICATIONS

Catalog Number

KTE60126

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Additional Info

Human Thymidylate synthetase (TS) ELISA Kit has high sensitivity and excellent specificity for detection of Human TS. No significant cross-reactivity or interference between Human TS and analogues was observed.

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