Human Thymus-specific serine protease (PRSS16) ELISA Kit

TSSP is thought to play a role in the alternative antigen presenting pathway used by cortical thymic epithelial cells during the positive selection of T cells. The gene is found in the large histone gene cluster on chromosome 6, near the major histocompatibility complex (MHC) class I region. A second transcript variant has been described, but its full length nature has not been determined.The deduced 514-amino acid PRSS16 protein, which the authors termed TSSP, has a calculated molecular mass of 55 kD. PRSS16 contains a putative N-terminal signal peptide and a prolylendopeptidase consensus sequence. Within its 3-prime untranslated region, it has 2 different polyadenylation sites. PRSS16 shares sequence similarity with prolylcarboxypeptidase (PRCP), particularly around the active-site serine.

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SPECIFICATIONS

Catalog Number

KTE61111

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

10279

Accession

Q9NQE7

Additional Info

Human Thymus-specific serine protease (PRSS16) ELISA Kit has high sensitivity and excellent specificity for detection of Human PRSS16. No significant cross-reactivity or interference between Human PRSS16 and analogues was observed.