Human Thyroid transcription factor 1 (TITF1) ELISA Kit

Cat no: KTE62625

Supplier: Abbkine Scientific Co.Ltd.

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Thyroid transcription factor-1 (TTF-1) is a protein that regulates transcription of genes specific for the thyroid, lung, and diencephalon. It is also known as thyroid specific enhancer binding protein. It is used in anatomic pathology as a marker to determine if a tumor arises from the lung or thyroid.TTF-1 positive cells are found in the lung as type II pneumocytes and Clara cells. In the thyroid, follicular and parafollicular cells are also positive for TTF-1.For lung cancers, adenocarcinomas are usually positive, while squamous cell carcinomas and large cell carcinomas are rarely positive. Small cell carcinomas (of any primary site) are usually positive. TTF1 is more than merely a clinical marker of lung adenocarcinoma. It plays an active role in sustaining lung cancer cells in view of the experimental observation that it is mutated in lung cancer.

Catalogue number:	KTE62625
Reactivities:	Human
Applications:	ELISA
Size:	48T, 96T, 96T5, 96T50
Accession:	P43698
Gene:	403940
Additional info:	Human Thyroid transcription factor 1 (TITF1) ELISA Kit has high sensitivity and excellent specificity for detection of Human TITF1. No significant cross-reactivity or interference between Human TITF1 and analogues was observed.

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Human Thyroid transcription factor 1 (TITF1) ELISA Kit

Cat no: KTE62625

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