Human Thyroxine-Binding Globulin (TBG) ELISA Kit

Thyroxine-binding globulin (TBG) binds Thyroid hormone in circulation. It is one of three proteins (along with transthyretin and albumin) responsible for carrying the thyroid hormones thyroxine (T4) and 3,5,3вЂ™-triiodothyronine (T3) in the bloodstream. Of these three proteins, TBG has the highest affinity for T4 and T3, but is present in the lowest concentration. Despite its low concentration, TBG carries the majority of T4 in serum. Due to the very low serum concentration of T4 & T3, TBG is rarely more than 25% saturated with its ligand. Unlike transthyretin and albumin, TBG has a single binding site for T4/T3. TBG is synthesized primarily in the liver as a 54 kDa protein. Genomically, TBG is a serpin, although it has no inhibitory function like many other members of this class of proteins.

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SPECIFICATIONS

Catalog Number

KTE60701

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

6906

Accession

P05543

Additional Info

Human Thyroxine-Binding Globulin (TBG) ELISA Kit has high sensitivity and excellent specificity for detection of Human SERPINA7. No significant cross-reactivity or interference between Human SERPINA7 and analogues was observed.