Human Tissue inhibitors of metalloproteinase 3 (TIMP3) ELISA Kit

TIMP3, The cDNAs contained a 591-bp open reading frame encoding 9 amino acid residues of the signal peptide and 188 residues of the mature TIMP3 polypeptide. Both the nucleotide sequence and the deduced translation product of the TIMP3 cDNA had a high degree of similarity to the TIMP1 and TIMP2 gene products, including 12 conserved cysteinyl residues at the same relative positions. The TIMP3 gene is expressed in many tissues, with highest expression in the placenta. Wilde et al. (1994) cloned and sequenced TIMP3 from phorbol ester-differentiated cells stimulated with bacterial lipopolysaccharide. The open reading frame encoded a 211-amino acid precursor, including a 23-residue secretion signal. The mature polypeptide had a calculated molecular weight of 21.6 kD.

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SPECIFICATIONS

Catalog Number

KTE60325

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

7078

Accession

P35625

Additional Info

Human Tissue inhibitors of metalloproteinase 3 (TIMP3) ELISA Kit has high sensitivity and excellent specificity for detection of Human TIMP3. No significant cross-reactivity or interference between Human TIMP3 and analogues was observed.