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Human Toll-like receptor 3 (TLR3) ELISA Kit

Cat no: KTE60315

Human Toll-like receptor 3 (TLR3) ELISA Kit

TLR 3 is a member of the Toll-like receptor family of pattern recognition receptors of the innate immune system. Discovered in 2001,TLR3 recognizes double-stranded RNA, a form of genetic information carried by some viruses such as reoviruses. Upon recognition, TLR 3 induces the activation of NF-kB to increase production of type I interferons which signal other cells to increase their antiviral defenses.\nDouble-stranded RNA is also recognised by the cytoplasmic receptors RIG-I and MDA-5.The structure of TLR3 was reported in June 2005 by researchers at The Scripps Research Institute. TLR3 forms a large horseshoe shape that contacts with a neighboring horseshoe, forming a "dimer" of two horseshoes.

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SPECIFICATIONS

Catalog Number

KTE60315

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

7098

Accession

O15455

Additional Info

Human Toll-like receptor 3 (TLR3) ELISA Kit has high sensitivity and excellent specificity for detection of Human TLR3. No significant cross-reactivity or interference between Human TLR3 and analogues was observed.

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