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Human Toll-like receptor 5 (TLR-5) ELISA Kit

Cat no: KTE60313

Human Toll-like receptor 5 (TLR-5) ELISA Kit

Toll-like receptor 5is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene product is expressed in myelomonocytic cells, and recognizes bacterial flagellin, a principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB and stimulates tumour necrosis factor-alpha production.

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SPECIFICATIONS

Catalog Number

KTE60313

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

7100

Accession

O60602

Additional Info

Human Toll-like receptor 5 (TLR-5) ELISA Kit has high sensitivity and excellent specificity for detection of Human TLR5. No significant cross-reactivity or interference between Human TLR5 and analogues was observed.

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