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Human Tolloid-like protein 2 (TLL2) ELISA Kit

Human Tolloid-like protein 2 (TLL2) ELISA Kit

Cat no: KTE60319

Supplier: Abbkine Scientific Co.Ltd.
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TLL2 encodes an astacin-like zinc-dependent metalloprotease and is a subfamily member of the metzincin family. Unlike other family members, a similar protein in mice does not cleave procollagen C-propeptides or chordin.TLL2 shares 80.3% amino acid sequence identity with BMP1, including 870 overlapping residues. Analysis by RT-PCR ELISA demonstrated weak expression of TLL2 in most tissues and moderate expression in heart and brain.TLL2 encodes a deduced 1,015-amino acid protein with a molecular mass of 120 kD by SDS/PAGE.Whereas BMP1, TLD, and TLL1 specifically process procollagen C-propeptides at the physiologically relevant site, TLL2 lacks this activity. BMP1 and TLL1 cleave chordin, but TLL2 and TLD do not.
Catalogue number: KTE60319
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: Q9Y6L7
Gene: 7093
Additional info: Human Tolloid-like protein 2 (TLL2) ELISA Kit has high sensitivity and excellent specificity for detection of Human TLL2. No significant cross-reactivity or interference between Human TLL2 and analogues was observed.

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