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Human Transforming growth factor ?3 (TGF-?3) ELISA Kit

Cat no: KTE60511

Human Transforming growth factor ?3 (TGF-?3) ELISA Kit

TGF-?3 encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. TGF-?3 is involved in embryogenesis and cell differentiation, and may play a role in wound healing. Mutations in TGF-?3 are a cause of aortic aneurysms and dissections, as well as familial arrhythmogenic right ventricular dysplasia 1.

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SPECIFICATIONS

Catalog Number

KTE60511

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

7043

Accession

P10600

Additional Info

Human Transforming growth factor ?3 (TGF-?3) ELISA Kit has high sensitivity and excellent specificity for detection of Human TGFB3. No significant cross-reactivity or interference between Human TGFB3 and analogues was observed.

SUPPLIER INFO

Abbkine Scientific Co.Ltd.

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