Human Transient receptor potential cation channel subfamily A member 1 (TRPA1) ELISA Kit

TRPA1 is a member of the transient receptor potential channel family. TRPA1, contains 14 N-terminal ankyrin repeats and is believed to function as a mechanical stress sensor. The specific function of this protein has not yet been determined; however, studies indicate the function may involve a role in signal transduction and growth control. Recent studies indicate that TRPA1 is activated by a number reactive compounds (allyl isothiocyanate, cinnamaldehyde, farnesyl thiosalicylic acid, Nicotine and its structural analogues formalin, hydrogen peroxide, 4-hydroxynonenal, and acrolein) and considered as a 'chemosensor' in the body. TRPA1 is considered as an attractive pain target based on the fact that TRPA1 knockout mice showed near complete attenuation of formalin-induced pain behaviors.

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SPECIFICATIONS

Catalog Number

KTE60133

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

8989

Accession

O75762

Additional Info

Human Transient receptor potential cation channel subfamily A member 1 (TRPA1) ELISA Kit has high sensitivity and excellent specificity for detection of Human TRPA1. No significant cross-reactivity or interference between Human TRPA1 and analogues was observed.