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Human Transportin-3 (TNPO3) ELISA Kit

Human Transportin-3 (TNPO3) ELISA Kit

Cat no: KTE60181

Supplier: Abbkine Scientific Co.Ltd.
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TNPO3 is a nuclear import receptor for serine/arginine-rich (SR) proteins, which are essential precursor-mRNA splicing factors.By yeast 2-hybrid analysis using the RS domain of the E2 protein of human papillomavirus (HPV)-5 as bait, Lai et al. (2000) cloned a TNPO3 splice variant, TRNSR2, from a HeLa cell cDNA library. The deduced 923-amino acid TRNSR2 protein lacks 2 regions of about 30 amino acids each found in the TRNSR protein identified by Kataoka et al. (1999). Northern blot analysis detected ubiquitous expression of a 4.5-kb transcript, with highest expression in testis. Epitope-tagged TRNSR2 localized throughout transfected HeLa cells, but a mutant lacking the N-terminal region colocalized with splicing factor SC35 (SFRS2) in nuclear speckles.
Catalogue number: KTE60181
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: Q9Y5L0
Gene: 23534
Additional info: Human Transportin-3 (TNPO3) ELISA Kit has high sensitivity and excellent specificity for detection of Human TNPO3. No significant cross-reactivity or interference between Human TNPO3 and analogues was observed.

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