Human Trinucleotide repeat-containing gene 6C protein (TNRC6C) ELISA Kit

By sequencing clones obtained from a fetal brain cDNA library, Nagase et al. (2000) cloned TNRC6C, which they designated KIAA1582. The deduced 1,448-amino acid protein contains an RNA recognition motif and a ubiquitin-associated (UBA) domain. RT-PCR ELISA detected moderate expression in heart, kidney, testis, ovary, adult and fetal brain, and all specific adult brain regions examined. Low expression was detected in skeletal muscle, and no expression was detected in lung, liver, pancreas, spleen, and fetal liver.\nSchneider et al. (2006) stated that the TNRC6C protein contains a glycine/tryptophan (GW)-rich N-terminal domain, followed by a UBA domain, a glutamine-rich region, and a C-terminal RNA recognition motif.

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SPECIFICATIONS

Catalog Number

KTE60175

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

57690

Accession

Q9HCJ0

Additional Info

Human Trinucleotide repeat-containing gene 6C protein (TNRC6C) ELISA Kit has high sensitivity and excellent specificity for detection of Human TNRC6C. No significant cross-reactivity or interference between Human TNRC6C and analogues was observed.