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Human Tripeptidyl-peptidase 1 (TPP1) ELISA Kit

Cat no: KTE60145

Human Tripeptidyl-peptidase 1 (TPP1) ELISA Kit

Tripeptidyl-peptidase 1 is a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity.\nIt is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome.Detected in all tissues examined with highest levels in heart and placenta and relatively similar levels in other tissues.

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SPECIFICATIONS

Catalog Number

KTE60145

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

1200

Accession

O14773

Additional Info

Human Tripeptidyl-peptidase 1 (TPP1) ELISA Kit has high sensitivity and excellent specificity for detection of Human TPP1. No significant cross-reactivity or interference between Human TPP1 and analogues was observed.

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