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Human Troponin I, slow skeletal muscle (TNNI1) ELISA Kit

Cat no: KTE60190


Supplier: Abbkine Scientific Co.Ltd.
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TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. The TnI-fast and TnI-slow genes are expressed in fast-twitch and slow-twitch skeletal muscle fibers, respectively, while the TnI-cardiac gene is expressed exclusively in cardiac muscle tissue. This gene encodes the Troponin-I-skeletal-slow-twitch protein. TNNI1 is expressed in cardiac and skeletal muscle during early development but is restricted to slow-twitch skeletal muscle fibers in adults. The encoded protein prevents muscle contraction by inhibiting calcium-mediated conformational changes in actin-myosin complexes.
Catalogue number: KTE60190
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: P19237
Gene: 7135
Additional info: Human Troponin I, slow skeletal muscle (TNNI1) ELISA Kit has high sensitivity and excellent specificity for detection of Human TNNI1. No significant cross-reactivity or interference between Human TNNI1 and analogues was observed.

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