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Human Tubulin polymerization-promoting protein (TPPP) ELISA Kit

Human Tubulin polymerization-promoting protein (TPPP) ELISA Kit

Cat no: KTE60144

Supplier: Abbkine Scientific Co.Ltd.
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Seki et al. (1999) cloned p25 from a neuroblastoma cDNA library. The deduced 219-amino acid protein has a calculated molecular mass of about 24 kD. Human and bovine p25 share 90% amino acid identity. In contrast to the brain-specific expression of bovine p25, RT-PCR detected human p25 in all tissues examined.Martin et al. (2002) found that p24 associated with Gsk3 in microtubules from adult rat brain. p24 bound Gsk3 and inhibited its kinase activity at low magnesium concentrations. p24 was a poor substrate for Gsk3, but it could be phosphorylated by other protein kinases. Bovine Tppp inhibited mitotic spindle assembly and nuclear envelope breakdown following injection into Drosophila embryos. It did not affect other cellular events.
Catalogue number: KTE60144
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: O94811
Gene: 11076
Additional info: Human Tubulin polymerization-promoting protein (TPPP) ELISA Kit has high sensitivity and excellent specificity for detection of Human TPPP. No significant cross-reactivity or interference between Human TPPP and analogues was observed.

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