Human Tumor necrosis factor-inducible gene 6 protein (TNFAIP6) ELISA Kit

TSG-6 is a 30 kDa secreted protein that contains a hyaluronan-binding LINK domain a and thus is a member of the hyaluronan-binding protein family, also called hyaladherins. The hyaluronan-binding domain is known to be involved in extracellular matrix stability and cell migration. This protein has been shown to form a stable, covalent complex with inter-alpha-inhibitor (I?I), and thus enhance the serine protease inhibitory activity of I?I, which is important in the protease network associated with inflammation. The expression of this gene can be induced by a number of signalling molecules, principally tumor necrosis factor ? (TNF-?) and interleukin-1 (IL-1). The expression can also be induced by mechanical stimuli in vascular smooth muscle cells, and is found to be correlated with proteoglycan synthesis and aggregation.

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SPECIFICATIONS

Catalog Number

KTE60233

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

7130

Accession

P98066

Additional Info

Human Tumor necrosis factor-inducible gene 6 protein (TNFAIP6) ELISA Kit has high sensitivity and excellent specificity for detection of Human TNFAIP6. No significant cross-reactivity or interference between Human TNFAIP6 and analogues was observed.