Human Tumor necrosis factor receptor superfamily member 12A (TNFRSF12A) ELISA Kit

Cat no: KTE60223

Supplier: Abbkine Scientific Co.Ltd.

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FN14 protein, which shares 82% amino acid identity with the mouse sequence, contains a signal peptide, an extracellular domain, a membrane-anchoring domain, and a cytoplasmic domain. Northern blot analysis detected increased FN14 expression in response to FGF1, calf serum, or phorbol ester stimulation of human quiescent fibroblasts in vitro. A 1.2-kb FN14 transcript was expressed at high levels in heart, placenta, and kidney, at intermediate levels in lung, skeletal muscle, and pancreas, and at low levels in brain and liver. In addition, elevated FN14 expression was found in human liver cancer cell lines and hepatocellular carcinoma specimens. Expression of mouse Fn14 was upregulated in hepatocellular carcinoma nodules that develop in 2 different transgenic mouse models of hepatocarcinogenesis.

Catalogue number:	KTE60223
Reactivities:	Human
Applications:	ELISA
Size:	48T, 96T, 96T5, 96T50
Accession:	Q9NP84
Gene:	51330
Additional info:	Human Tumor necrosis factor receptor superfamily member 12A (TNFRSF12A) ELISA Kit has high sensitivity and excellent specificity for detection of Human TNFRSF12A. No significant cross-reactivity or interference between Human TNFRSF12A and analogues was observed.

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Human Tumor necrosis factor receptor superfamily member 12A (TNFRSF12A) ELISA Kit

Cat no: KTE60223

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