Human Tumor necrosis factor receptor superfamily member 13B (TNFRSF13B) ELISA Kit

Tumor necrosis factor receptor superfamily member 13B, also known as TNFRSF13B or more commonly as TACI, is a transmembrane receptor protein found predominantly on the surface of B cells, which are an important part of the immune system.TACI is a lymphocyte-specific member of the tumor necrosis factor (TNF) receptor superfamily. It was orignially discovered because of its ability to interact with calcium-modulator and cyclophilin ligand (CAML). TACI was later found to play a crucial role in humoral immunity by interacting with two members of the TNF family: BAFF and APRIL. These proteins signal through TACI inducing activation of several transcription factors including NFAT, AP-1, and NF-kappa-B which then modulate cellular activities. Defects in the function of TACI can lead to immune system diseases.

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SPECIFICATIONS

Catalog Number

KTE60222

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

23495

Accession

O14836

Additional Info

Human Tumor necrosis factor receptor superfamily member 13B (TNFRSF13B) ELISA Kit has high sensitivity and excellent specificity for detection of Human TNFRSF13B. No significant cross-reactivity or interference between Human TNFRSF13B and analogues was observed.